Quickest 3h 1min
There are 1 train company operating 4 routes - ICE50, CNL 1258, ICE20, ICE12, 4 buses from Weimar to Maintal. The cheapest train costs $21 and is 3h 3min.
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There are 3 ways to travel from Weimar to Maintal. 1 train, 4 buses and 1 by car are possible between the two areas. The by car from Weimar to Maintal is the cheapest. The train operated by DB running from Hopfgarten (Weimar) to Maintal West is the fastest. The train operated by DB running from Weimar West to Maintal Ost is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!