Quickest 2h 53min
There are 1 bus2 train companies operating 5 routes - TER 3, TGV 522, FR-830, TGV 505, TGV Lyria from Villeurbanne to Besançon. The cheapest train costs $46 and is 3h 44min.
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There are 3 ways to travel from Villeurbanne to Besançon. 1 bus, 2 trains and 1 by car are possible between the two areas. The by car from Villeurbanne to Besançon is the cheapest. The by car from Villeurbanne to Besançon is the fastest. The train operated by SNCF running from Lyon Gorge de Loup to Besançon Viotte is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!