Quickest 5h 3min
There are 2 buses1 train company operating 6 routes - IC 732, TER 19, TER 03/5, FR-830, TER 01/26, IC 417, 1 flight from Villefranche-sur-Saone to Tours. The cheapest train costs $55 and is 5h 34min.
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There are 4 ways to travel from Villefranche-sur-Saone to Tours. 2 buses, 2 trains, 1 flight and 1 by car are possible between the two areas. The by car from Villefranche-sur-Saone to Tours is the cheapest. The flight from LYS to TUF is the fastest. The train operated by running from Villefranche-sur-Saône to Tours is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!