Quickest 7h 29min
There are 1 train company operating 3 routes - Silver Star, Acela Express, Shuttle, 3 buses and 3 flights from STM to HOL. The cheapest train costs $210 and is 1d 1h 5min.
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There are 4 ways to travel from STM to HOL. 4 trains, 3 buses, 3 flights and 1 by car are possible between the two areas. The by car from STM to HOL is the cheapest. The flight from LGA to FLL is the fastest. The train operated by Amtrak running from NRO to HOL is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!