Quickest 2h 52min
There are 4 buses1 train company operating 2 routes - Línea 77, C-3 from Santa Cruz de Mudela to Madrid. The cheapest train costs $43 and is 2h 52min.
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There are 3 ways to travel from Santa Cruz de Mudela to Madrid. 4 buses, 1 train and 1 by car are possible between the two areas. The by car from Santa Cruz de Mudela to Madrid is the cheapest. The train operated by Renfe running from Santa Cruz de Múdela to Aranjuez is the fastest. The train operated by Renfe running from Santa Cruz de Múdela to Madrid Atocha is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!