Quickest 7h 24min
There are 3 buses1 train company operating 2 routes - Texas Eagle, Empire Builder, and 3 flights from San Antonio to Saint Paul. The cheapest train costs $256 and is 1d 7h 7min.
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There are 4 ways to travel from San Antonio to Saint Paul. 3 buses, 4 trains, 3 flights and 1 by car are possible between the two areas. The by car from San Antonio to Saint Paul is the cheapest. The flight from AUS to MSP is the fastest. The train operated by Amtrak running from SAS to MSP is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!