Quickest 5h 20min
There are 2 buses1 train company operating 2 routes - IC62, ICE11, 1 flight from Salzburg to Kassel. The cheapest train costs $115 and is 8h 36min.
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There are 4 ways to travel from Salzburg to Kassel. 2 buses, 1 train, 1 flight and 1 by car are possible between the two areas. The by car from Salzburg to Kassel is the cheapest. The flight from SZG to KSF is the fastest. The train operated by running from Salzburg to Kassel is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!