Quickest 3h 2min
There are 1 train company operating 2 routes - Intercités Bordeaux - Toulouse, 640, 1 bus from Saintes to Agen. The cheapest train costs $43 and is 3h 2min.
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There are 3 ways to travel from Saintes to Agen. 2 trains, 1 bus and 1 by car are possible between the two areas. The by car from Saintes to Agen is the cheapest. The train operated by SNCF running from Pons to Agen is the fastest. The train operated by SNCF running from Saintes to Agen Payou is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!