Quickest 7h 25min
There are 1 train company operating 3 routes - Adirondack, Crescent, Vermonter, 4 buses and 3 flights from RSP to TCL. The cheapest train costs $226 and is 1d 3h 15min.
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There are 4 ways to travel from RSP to TCL. 3 trains, 4 buses, 3 flights and 1 by car are possible between the two areas. The by car from RSP to TCL is the cheapest. The flight from BTV to BHM is the fastest. The train operated by Amtrak running from RSP to TCL is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!