Quickest 7h 30min
There are 4 buses3 flights1 train company operating 3 routes - Pacific Surfliner, Sunset Limited, Coast Starlight from Piedras Negras to Thousand Oaks. The cheapest train costs $211 and is 1d 1h 16min.
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There are 4 ways to travel from Piedras Negras to Thousand Oaks. 4 buses, 3 flights, 3 trains and 1 by car are possible between the two areas. The by car from Piedras Negras to Thousand Oaks is the cheapest. The flight from PDS to SNA is the fastest. The train operated by Amtrak running from DRT to MPK is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!