Quickest 2h 50min
There are 1 train company operating 4 routes - ICE91, ICE41, R5, 931, 4 buses from Passau to Nuremberg. The cheapest train costs $36 and is 3h 28min.
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There are 3 ways to travel from Passau to Nuremberg. 2 trains, 4 buses and 1 by car are possible between the two areas. The by car from Passau to Nuremberg is the cheapest. The train operated by DB running from Vilshofen (Niederbay) to Nürnberg Hbf (U-Bahn) is the fastest. The train operated by DB running from Passau Hbf to Nuremberg is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!