Quickest 7h 35min
There are 3 buses 4 flights1 train company operating 2 routes - Texas Eagle, California Zephyr from Odessa to Reno. The cheapest train costs $514 and is 2d 17h 19min.
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There are 4 ways to travel from Odessa to Reno. 3 buses, 4 flights, 3 trains and 1 by car are possible between the two areas. The by car from Odessa to Reno is the cheapest. The flight from HOB to SMF is the fastest. The train operated by Amtrak running from SND to RNO is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!