Quickest 7h 23min
There are 1 train company operating 3 routes - California Zephyr, Hiawatha Service, Empire Builder, 3 buses and 3 flights from MKE to GJT. The cheapest train costs $225 and is 1d 3h 2min.
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There are 4 ways to travel from MKE to GJT. 3 trains, 3 buses, 3 flights and 1 by car are possible between the two areas. The by car from MKE to GJT is the cheapest. The flight from MSN to GJT is the fastest. The train operated by Amtrak running from MKE to GJT is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!