Quickest 7h 26min
There are 4 flights1 train company operating 2 routes - Cardinal, Southwest Chief, and 3 buses from MHK to AVP. The cheapest train costs $220 and is 1d 2h 23min.
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There are 4 ways to travel from MHK to AVP. 4 flights, 3 trains, 3 buses and 1 by car are possible between the two areas. The by car from MHK to AVP is the cheapest. The flight from MHK to ELM is the fastest. The train operated by Amtrak running from TOP to NWK is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!