Quickest 3h 5min
There are 1 train company operating 3 routes - ICE82, ICE11, ICE42, 4 buses from Kaiserslautern to Ulm. The cheapest train costs $42 and is 4h 44min.
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There are 3 ways to travel from Kaiserslautern to Ulm. 1 train, 4 buses and 1 by car are possible between the two areas. The by car from Kaiserslautern to Ulm is the cheapest. The by car from Kaiserslautern to Ulm is the fastest. The train operated by running from Hochspeyer to Ulm is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!