Quickest 7h 34min
There are 4 flights 4 buses from IGU to SCL.
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There are 2 ways to travel from IGU to SCL. 4 flights and 4 buses are possible between the two areas. The bus from Puerto Iguazú to Santiago is the cheapest and fastest.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!