Quickest 7h 26min
There are 4 flights1 train company operating 2 routes - Sunset Limited, Crescent, and 3 buses from IAH to CHO. The cheapest train costs $217 and is 1d 1h 57min.
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There are 4 ways to travel from IAH to CHO. 4 flights, 3 trains, 3 buses and 1 by car are possible between the two areas. The by car from IAH to CHO is the cheapest. The flight from IAH to LYH is the fastest. The train operated by Amtrak running from HOS to CVS is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!