Quickest 2h 11min
There are 1 flight1 train company operating 4 routes - ICE10, RE7, RE1, RB81 from HHN to DTM. The cheapest train costs $68 and is 2h 44min.
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There are 3 ways to travel from HHN to DTM. 1 flight, 1 train and 1 by car are possible between the two areas. The by car from HHN to DTM is the cheapest. The train from Reil to Unna is the fastest. The train operated by DB running from Reil to Holzwickede is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!