Quickest 7h 34min
There are 4 buses 3 flights1 train company operating 2 routes - Southwest Chief, Cardinal from Hempstead to Kansas City. The cheapest train costs $215 and is 1d 1h 42min.
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There are 4 ways to travel from Hempstead to Kansas City. 4 buses, 3 flights, 3 trains and 1 by car are possible between the two areas. The by car from Hempstead to Kansas City is the cheapest. The flight from LGA to MCI is the fastest. The train operated by Amtrak running from NYP to KCY is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!