Quickest 7h 28min
There are 4 buses 3 flights1 train company operating 3 routes - Southwest Chief, Cardinal, Capitol Limited from Harrisburg to Wichita. The cheapest train costs $216 and is 1d 1h 56min.
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There are 4 ways to travel from Harrisburg to Wichita. 4 buses, 3 flights, 3 trains and 1 by car are possible between the two areas. The by car from Harrisburg to Wichita is the cheapest. The flight from SCE to ICT is the fastest. The train operated by Amtrak running from BAL to NEW is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!