Quickest 7h 31min
There are 3 buses1 train company operating 2 routes - Silver Star, Vermonter, and 3 flights from Hanover to Daytona Beach. The cheapest train costs $213 and is 1d 1h 29min.
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There are 4 ways to travel from Hanover to Daytona Beach. 3 buses, 4 trains, 3 flights and 1 by car are possible between the two areas. The by car from Hanover to Daytona Beach is the cheapest. The flight from MHT to DAB is the fastest. The train operated by Amtrak running from WRJ to DLD is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!