Quickest 3h 5min
There are 4 buses1 train company operating 4 routes - ICE41, ICE42, ICE11, ICE10, and 2 flights from Hanau to Essen. The cheapest train costs $36 and is 3h 26min.
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There are 4 ways to travel from Hanau to Essen. 4 buses, 1 train, 2 flights and 1 by car are possible between the two areas. The by car from Hanau to Essen is the cheapest. The by car from Hanau to Essen is the fastest. The train operated by DB running from Hanau Hbf to Essen-Frohnhausen is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!