Quickest 3h 40min
There are 1 bus company operating from Fuenlabrada to Oviedo, 1 airline operating from Fuenlabrada to Oviedo from Fuenlabrada to Oviedo. The cheapest bus costs $36 and is 5h 15min. The cheapest flight costs $98 and is 7h 50min.
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There are 3 ways to travel from Fuenlabrada to Oviedo. 4 buses, 1 flight and 1 by car are possible between the two areas. The by car from Fuenlabrada to Oviedo is the cheapest. The flight operated by Vueling Airlines running from MAD to OVD is the fastest. The bus operated by ALSA running from Estación Madrid Sur to Estación de Autobuses de Oviedo is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!