Quickest 7h 33min
There are 4 buses 3 flights1 train company operating 2 routes - California Zephyr, Capitol Limited from Fort Collins to Toledo. The cheapest train costs $217 and is 1d 2h 2min.
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There are 4 ways to travel from Fort Collins to Toledo. 4 buses, 3 flights, 3 trains and 1 by car are possible between the two areas. The by car from Fort Collins to Toledo is the cheapest. The flight from DEN to TOL is the fastest. The train operated by Amtrak running from DEN to TOL is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!