Quickest 2h 32min
There are 1 airline operating from EAS to SDR, 1 bus company operating from EAS to SDR from EAS to SDR. The cheapest flight costs $112 and is 16h 10min. The cheapest bus costs $17 and is 3h 0min.
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There are 3 ways to travel from EAS to SDR. 2 flights, 4 buses and 1 by car are possible between the two areas. The by car from EAS to SDR is the cheapest. The by car from EAS to SDR is the fastest. The bus operated by ALSA running from Estación de Autobuses de San Sebastian to Santander is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!