Quickest 4h 45min
There are 4 buses1 train company operating 2 routes - Cardinal, Texas Eagle, 1 airline operating from Eagle Pass to Indianapolis from Eagle Pass to Indianapolis. The cheapest train costs $241 and is 1d 5h 12min. The cheapest flight costs $192 and is 4h 45min.
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There are 4 ways to travel from Eagle Pass to Indianapolis. 4 buses, 3 trains, 3 flights and 1 by car are possible between the two areas. The bus from Eagle Pass to Lafayette is the cheapest and fastest. The train operated by Amtrak running from DRT to IND is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!