Quickest 5h 42min
There are 1 train company operating 2 routes - ICE41, R3, 4 buses from Düsseldorf to Bayreuth. The cheapest train costs $68 and is 7h 31min.
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There are 3 ways to travel from Düsseldorf to Bayreuth. 3 trains, 4 buses and 1 by car are possible between the two areas. The by car from Düsseldorf to Bayreuth is the cheapest. The by car from Düsseldorf to Bayreuth is the fastest. The train operated by running from Düsseldorf to Bayreuth is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!