Quickest 7h 28min
There are 4 buses1 train company operating 2 routes - Maple Leaf, Silver Star, and 3 flights from Buffalo to West Palm Beach. The cheapest train costs $249 and is 1d 6h 12min.
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There are 4 ways to travel from Buffalo to West Palm Beach. 4 buses, 3 trains, 3 flights and 1 by car are possible between the two areas. The by car from Buffalo to West Palm Beach is the cheapest. The flight from JHW to PBI is the fastest. The train operated by Amtrak running from BFX to WPB is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!