Quickest 2h 54min
There are 1 flight1 train company operating 2 routes - IC I, M tranche 2, and 4 buses from BRU to LUX. The cheapest train costs $22 and is 3h 34min.
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There are 4 ways to travel from BRU to LUX. 1 flight, 4 trains, 4 buses and 1 by car are possible between the two areas. The by car from BRU to LUX is the cheapest. The by car from BRU to LUX is the fastest. The train operated by running from Evere to Luxembourg is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!