Quickest 7h 34min
There are 4 buses1 train company operating 2 routes - Maple Leaf, Crescent, 3 flights from Toronto to Baton Rouge. The cheapest train costs $275 and is 1d 9h 44min.
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There are 4 ways to travel from Toronto to Baton Rouge. 4 buses, 3 trains, 3 flights and 1 by car are possible between the two areas. The by car from Toronto to Baton Rouge is the cheapest. The flight from YYZ to BTR is the fastest. The train operated by Amtrak running from TWO to NOL is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!