There are 3 ferry companies operating from Sitia to Piraeus, 4 flights from Sitia to Piraeus. The cheapest ferry costs $62 and is 9h 0min.
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There are 2 ways to travel from Sitia to Piraeus. 4 ferries and 4 flights are possible between the two areas. The ferry operated by ANEK Superfast running from Heraklion to Piraeus is the cheapest. The ferry operated by Anek Lines running from Karpathos to Piraeus is the fastest. The ferry operated by Anek Lines running from Sitia to Piraeus is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!