Quickest 7h 35min
There are 4 buses1 train company operating 2 routes - Texas Eagle, California Zephyr, 3 flights from Reno to Odessa. The cheapest train costs $514 and is 2d 17h 19min.
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There are 4 ways to travel from Reno to Odessa. 4 buses, 3 trains, 3 flights and 1 by car are possible between the two areas. The by car from Reno to Odessa is the cheapest. The flight from RNO to MAF is the fastest. The train operated by Amtrak running from RNO to SND is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!