Quickest 3h 4min
There are 2 train companies operating 2 routes - VT D, Cross Country, 4 buses1 flight from Prestatyn to Middlesbrough. The cheapest train costs $96 and is 5h 1min.
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There are 4 ways to travel from Prestatyn to Middlesbrough. 2 trains, 4 buses, 1 flight and 1 by car are possible between the two areas. The by car from Prestatyn to Middlesbrough is the cheapest. The by car from Prestatyn to Middlesbrough is the fastest. The train operated by running from Prestatyn to Darlington is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!