There are 2 train companies operating 6 routes - ICE41, ICE11, S1, RE3, ICE12, ICE42. The cheapest train costs $36 and is 3h 27min.
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There are 4 ways to travel from Oberhausen to Frankfurt am Main. 4 buses, 3 trains, 1 flight and 1 by car are possible between the two areas. The by car from Oberhausen to Frankfurt am Main is the cheapest and fastest. The train operated by DB running from Oberhausen Hbf to Frankfurt (M) Taunusanlage is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!