Quickest 3h 51min
There are 2 train companies operating 7 routes - EC62, ICE11, ICE41, ICE42, ICE12, IC60, AZ1385 from Munich to Frankfurt am Main. The cheapest train costs $30 and is 4h 24min.
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There are 4 ways to travel from Munich to Frankfurt am Main. 4 trains, 3 buses, 1 flight and 1 by car are possible between the two areas. The by car from Munich to Frankfurt am Main is the cheapest. The train operated by DB running from München Marienplatz to Frankfurt am Main is the fastest. The train operated by running from München Marienplatz to Frankfurt am Main is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!