There are 1 train company operating 3 routes - VT E, VT F, VT B. The cheapest train costs $68 and is 2h 53min.
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There are 3 ways to travel from Manchester to Dumfries. 4 buses, 2 trains and 1 by car are possible between the two areas. The by car from Manchester to Dumfries is the cheapest. The train operated by Virgin Trains running from Ince to Lockerbie is the fastest. The train operated by running from Manchester to Lockerbie is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!