There are 2 train companies operating 2 routes - RE 50, RB61. The cheapest train costs $42 and is 3h 38min.
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There are 3 ways to travel from Leipzig to Liberec. 2 buses, 2 trains and 1 by car are possible between the two areas. The by car from Leipzig to Liberec is the cheapest and fastest. The train operated by running from Leipzig to Zittau is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!