Quickest 7h 34min
There are 3 buses1 train company operating 2 routes - Capitol Limited, Silver Star, 3 flights from Lakeland to Madison. The cheapest train costs $263 and is 1d 8h 7min.
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There are 4 ways to travel from Lakeland to Madison. 3 buses, 3 trains, 3 flights and 1 by car are possible between the two areas. The by car from Lakeland to Madison is the cheapest. The flight from MCO to MSN is the fastest. The train operated by Amtrak running from LKL to CHI is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!