There are 1 train company operating 4 routes - RB49, RE2, RE1, ICE82. The cheapest train costs $32 and is 2h 32min.
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There are 3 ways to travel from Heilbronn to Kaiserslautern. 2 buses, 2 trains and 1 by car are possible between the two areas. The by car from Heilbronn to Kaiserslautern is the cheapest. The by car from Heilbronn to Kaiserslautern is the fastest. The train operated by running from Heilbronn to Kaiserslautern is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!