There are 1 train company operating 5 routes - CNL 1258, 739, 739, 739, 739. The cheapest train costs $145 and is 6h 20min.
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There are 3 ways to travel from Heidelberg to Meersburg. 1 train, 4 buses and 1 by car are possible between the two areas. The by car from Heidelberg to Meersburg is the cheapest and fastest. The train operated by running from Heidelberg to Uhldingen-Mühlhofen is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!