Quickest 4h 25min
There are 1 train company operating 7 routes - EC62, ICE11, ICE41, ICE42, ICE20, IC60, IC62 from Frankfurt am Main to Munich. The cheapest train costs $31 and is 4h 29min.
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There are 4 ways to travel from Frankfurt am Main to Munich. 3 buses, 4 trains, 1 flight and 1 by car are possible between the two areas. The by car from Frankfurt am Main to Munich is the cheapest. The train operated by DB running from Frankfurt am Main to Munich is the fastest. The train operated by DB running from Frankfurt (M) Taunusanlage to München Marienplatz is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!