Quickest 3h 4min
There are 4 buses1 train company operating 3 routes - RE7, ICE12, ICE11 from Dessau to Kassel. The cheapest train costs $66 and is 6h 27min.
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There are 3 ways to travel from Dessau to Kassel. 4 buses, 2 trains and 1 by car are possible between the two areas. The by car from Dessau to Kassel is the cheapest. The by car from Dessau to Kassel is the fastest. The train operated by running from Dessau to Kassel is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!