There are 2 train companies operating 2 routes - 135 (GW), ECML. The cheapest train costs $62 and is 4h 22min.
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There are 3 ways to travel from Andover to Grantham. 4 buses, 2 trains and 1 by car are possible between the two areas. The by car from Andover to Grantham is the cheapest. The by car from Andover to Grantham is the fastest. The train operated by running from Bedwyn to Grantham is the most convenient.
It's important to check each mode when booking your ticket so that you can find the best method for you. The cost of each type varies differently, so be sure to use Faretrotter to keep an eye out!